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Table 1 EGF- and/or TNF-responsive chemokines and chemokine receptors obtained in ovarian cancer cell lines

From: Characteristics of chemokine signatures elicited by EGF and TNF in ovarian cancer cells

  OVCAR-3 SKOV-3 CaOV-3 TOV-21G
Chemokine EGF TNF ET EGF TNF ET EGF TNF ET EGF TNF ET
CCL2 2.95 7.01 12.86        1.28 -1.03 1.38
CCL20 2.20 3.41 7.19 3.68 2.96 23.26 2.66 1.20 3.10    
CCL25        1.02 1.37 1.43 1.31 1.39 1.17
CCL26     -1.44 -1.11 1.02       
CCL28 1.77 1.55 1.42 -1.06 -1.02 -1.08 -1.09 1.21 1.06 -1.11 1.21 -1.25
CXCL1 2.53 4.38 6.48 2.64 8.03 10.56 1.72 1.59 2.25 3.02 1.07 3.23
CXCL2 3.43 4.99 8.97 1.87 13.98 12.82 5.82 1.83 7.67 4.81 1.04 5.82
CXCL3 2.81 6.73 9.68 1.45 9.09 10.85 1.30 1.55 1.82 2.80 1.25 3.51
CXCL5           1.28 -1.00 1.33
CXCL8 3.73 4.38 11.67 6.19 9.75 35.02 5.74 1.90 9.85 5.15 1.00 5.74
CXCL12           -1.33 1.26 -1.13
CXCL14        -1.24 1.19 -1.04 -1.14 1.23 -1.03
CXCL16 2.40 2.50 2.74 -1.02 1.00 -1.23 1.12 1.33 1.09 -1.04 1.20 -1.09
Receptor             
CCR10           -1.36 1.14 -1.25
CXCR4        1.32 1.70 1.62 1.38 1.15 1.27
CXCR5        5.24 3.33 10.63    
CXCR6           1.08 1.24 -1.06
CXCR7        -1.10 -1.04 -1.44    
  1. Only PCR array data for highly expressed chemokines and chemokine receptors (below an average threshold cycle of 30) are described above. Values shown represent the fold changes over baseline values, in the presence of EGF, TNF or both (ET). Bold numbers indicate EGF- or TNF-responsive chemokines and chemokine receptors levels that were elevated > 2-fold among highly expressed chemokines. Bold underlined numbers indicate the presence of a significant synergism when both EGF and TNF were added.