Figure 7

Inhibition of proinflammatory cytokine response of THP-1 monocytes activated with LPS using a pAb anti-PRLr. IL-1β, IL-6, TNF-a and IL-10 were assayed in culture supernatants of THP-1 monocytes activated with LPS alone or including pAb anti-PRLr (MAB1167) after 48 h. Differences among untreated cells vs. LPS treated are considered significant as p<0.05*; p<0.001***; or between cell cultures treated with LPS alone versus LPS and pAb anti-PRLr as p<0.05†; p<0.001†††.