Figure 4

ELISA analysis of IL-6 expression in the airway epithelial cells. The effect of HDAC inhibitors on IL-6 production in the NCI-H292 cells (A) and the primary nasal epithelial cells (B) in response to poly(I:C) stimulation. Cells were pretreated respectively with TSA (200 nM) or SB(4 mM) for 2 h prior to the poly(I:C) (20 ug/ml) stimulation for 24 h. IL-6 production in cell supernatant was analyzed using ELISA. *p<0.05 vs control. Values represent the mean±SD of three independent experiments.