Figure 3

Effects of XH-14 on LPS-induced inflammatory cytokine production in murine macrophages. RAW 264.7 cells were treated with 0–20 μM of XH-14 in the presence of 100 ng/ml LPS or with LPS alone for 24 h. The cell culture media were then collected, and the amount of (Α) IL-1β and (B) IL-6 released was measured. The results are reported as mean ± SEM of three independent experiments in triplicate. Statistical significance is based on the difference when compared with LPS-stimulated cells (^*P < 0.05, ^***P < 0.001).