From: Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity
Gene
Mean (Fold Change)
SEM
p-Value
IL-1β
246.34
48.12
<0.001
IL-6
2895.17
1571.28
IL-8
241.89
56.71
MMP1
166.05
31.06
MMP3
260.58
70.75
MMP13
119.06
29.49
TNF-α
21.45
7.16
TLR2
8.49
1.64