Figure 2From: Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activityEffects of the curcuma DMSO extract (2a) and curcuma ethanol extract (2b) on mRNA levels of candidate genes after 6 hours, indicated as fold change relative to IL-1β-treatment (IL-1β treated cells also contain 0.03% of DMSO or EtOH respectively). Data was obtained by real-time RT-PCR (2-ΔΔCt method) and is presented as Mean and SEM (n = 5). Asterisks indicate statistical significance (p < 0.05). Each gene was normalized to its respective IL-1β treatment (IL-1β + solvent), which was always set to 100% (only one exemplary control bar is shown).Back to article page